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Protein Engineering & Development ================================= #Proteinengineering is the process or a procedure of developing useful or valuable proteins. It is an interdisciplinary subject in the field of life sciences in this study of various kind of protein structures, interactions, #protein folding and also designing of protein principles can be done. There are to two are present for protein engineering those are A. Rational protein design B. Direct evolution design
Rare andUndiagnosed Diseases ============================== #Rare diseasesand Undiagnosed diseases are the diseases that affects the small number of people or small percentage of population. Many rare diseases appeared early in life, and about 30 percent of children with rare diseases will die before reaching their 5th birthday. These are mostly #geneticdisorders. Next-generation sequencing (NGS) technology is used to discover the Rare and Undiagnosed Diseases.
#Molecular Biology is an interdisciplinary subject in biology it is a combination of subjects like Biochemistry, Genetics, Bioinformatics, Computational biology .It deals with the molecular activity processes like replication, #transcription, translation, and cell function. Various Emerging Technologies were developed in Molecular biology those are like 1) Organic electronics 2) #Nutrigenomics 3) Signaling Technology
#Molecular Biochemistry is the study of the molecular mechanisms by which genetic information encoded in DNA is able to result in the processes of life. Molecular Biochemistry has developed widely to capture the array of #chemistry, physics, medicine and biology. It is one of the most important aspects of molecular biology to discover the #chemical properties of the molecules.
Modern genetics has expanded beyond #inheritance to study the function and behavior of genes and gene structure and function, variation, and distribution are studied within the context of the cell, the organism and within the context of the population #Genetic engineering is the process of manually adding new #DNA to an organism.
Genomics &Proteomics ======================== #Genomics is the study of entire genomes and theirs roles, function, importance and related techniques in inheritance. Genomics also involves in study of intra genomic processes like #epistasis, pleiotropy and as well as the interactions between loci and alleles within the genome. #Proteomics is large the scale study of a specific proteome, including information on protein abundances..
RNA-Based Therapeutic Approaches ================================= #RNA-based therapeutics can be classified based on the mechanism of activity, and it include inhibitors of mRNA translation, the agents of RNA interference (RNAi), catalytically active RNA molecules, and RNAs that bind #proteins and other molecular #ligands. RNA therapeutics have improvements in synthetic and natural nucleic acid carriers and the development of chemically modified oligonucleotides.
Cell Signaling, Kinase and Chemotherapy ===================================== #Cell signaling is the process of communication that governs the basic activities of cells and coordinates cell actions. Cells can communicate by using chemical signals. These #chemical signals, may be proteins or other molecules produced by a sending cell, are often secreted from the cell and released into the extracellular space.
Tissue Engineering and GenomeEngineering ======================================= #Tissue Engineering can be defined as use of living cells, material and engineering methods, and use of biochemical factors and physicochemical factors, to improve or replace the #biological tissues. The main aim of the tissue engineering is to assemble functional constructs that restore, maintain, or improve damaged tissues or whole organs.
Bioinformatics and Drug Designing ================================ #Bioinformatics is an interdisciplinary field of science it develops the methods and software tools for an understanding of biological data. It is combination subjects like computer science, statistics, mathematics, and engineering. It is has been used in #in silico analyses of biological queries using mathematical and statistical techniques.
Computational Molecular Biology ================================= #Computational Molecular Biology is an interdisciplinary subject in field of science it mainly focuses on the computational, statistical, experimental, and technological methods, which is accelerating the discovery of new technologies and tools for molecular biology. In computational molecular biology we can understand the major issues concerning analysis of #genomes, sequences and structures of molecules.
Techniques used in Molecular Biology =================================== In Molecular Biology several techniques are used those are given below # Molecular cloning or Expression cloning Polymerase Chain Reaction electrophoresis
#MitochondrialGenetics is the study of genetics of mitochondrial DNA. In most multi cellular organisms, mitochondrial DNA is inherited only from the mother's ovum. #Mitochondrial DNA mutations lead to functional problems, which may causes muscle disorders. Mitochondrial DNA is used in electron transport chain, replication, #transcription, and translation.