Expert advice to help you cure dry mouth (Xerostomia) --- Most commonly, dry mouth is a result of dehydration or a side effect of oral medications. It can also be associated as a result of damage to salivary glands though injury, surgical damage, or head/neck radiation therapy. Beyond the uncomfortable feeling of dry mouth, lack of treating the reason and symptoms can lead to more oral health issues. Keep in mind this advice to help cure your dry mouth.