Laudanum: alcoholic tincture of opium, sometimes sweetened with sugar (also called wine of opium). The century was marked by a widespread use: cheaper than a bottle of wine and not taxed as an alcoholic beverage. The addictive properties were not known.
1885 -- Anandibai Joshi of India, Keiko Okami of Japan, and Sabat Islambouli of Syria -- each became the first licensed female doctors in their respective countries. The three were students at the Women’s Medical College of Pennsylvania.