CADASIL INFORMATION FOR PATIENTS AND FAMILIES What does CADASIL stand for? CADASIL is the abbreviation for Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leucoencephalopathy. This complicated phrase summarises the main medical features - that it is an inherited condition leading to changes in blood vessels, which may result in strokes and other changes in the brain. What does "Autosomal Dominant" mean? This is a particular pattern of genetic inheritance.