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The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have reversed the process, recreating a youthful brain that facilitated both learning and healing in the adult mouse.

Flip of a single molecular switch makes an old mouse brain young

The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have reversed the process, recreating a youthful brain that facilitated both learning and healing in the adult mouse.

Dr. Thomas J. Deerinck  National Center for Microscopy and Imaging Research  La Jolla, California, USA    Sagittal section of rat cerebellum (40x)  Fluorescence and Confocal

Dr. Thomas J. Deerinck National Center for Microscopy and Imaging Research La Jolla, California, USA Sagittal section of rat cerebellum (40x) Fluorescence and Confocal

Neurons (in blue to yellow) growing on top of astrocytes (in red, helper cells within the nervous system) in a human stem cell embryoid body (a cluster of differentiating human embryonic stem cells).

Neurons (in blue to yellow) growing on top of astrocytes (in red, helper cells within the nervous system) in a human stem cell embryoid body (a cluster of differentiating human embryonic stem cells).

http://cdn.thetechjournal.com/wp-content/uploads/HLIC/798ace6285a8ef83e36ebc0667823b99.jpg

http://cdn.thetechjournal.com/wp-content/uploads/HLIC/798ace6285a8ef83e36ebc0667823b99.jpg

Genomics: Sequencing DNA from individual cells is changing the way researchers think of humans as a whole

Genomics: Sequencing DNA from individual cells is changing the way researchers think of humans as a whole

Sincell – for statistical assessment of cell-state hierarchies from single-cell RNA-Seq

Flatmount of astrocytes in the nerve fiber layer of the mouse retina | 2011 Photomicrography Competition | Nikon Small World

Flatmount of astrocytes in the nerve fiber layer of the mouse retina | 2011 Photomicrography Competition | Nikon Small World

Educación Kreadis: La influencia de los conflictos parentales en los hijos. http://educakreadis.blogspot.com.es/2014/11/la-influencia-de-los-conflictos.html

Educación Kreadis: La influencia de los conflictos parentales en los hijos. http://educakreadis.blogspot.com.es/2014/11/la-influencia-de-los-conflictos.html

Category: High-content analysis. Image description: 3T3-L1 derived adipocytes stained for lipid droplets (green) and DNA (blue). Therapeutic focus: Obesity.

Category: High-content analysis. Image description: 3T3-L1 derived adipocytes stained for lipid droplets (green) and DNA (blue). Therapeutic focus: Obesity.

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