Christina, Queen of Sweden (1626-1689), abdicated and adopted name Christina Alexandra. Christina was moody, intelligent, and interested in books and manuscripts, religion, alchemy, and science. Possibly intersexed. [says Wikipedia].
Queen Margaret Navarre. was born on April 11th, 1492. Her brother was Francis I, King of France. In 1525 she married Henry, King of Navarre. To learn more on her go to:http://reformingtoscripture.com/resources/articles/008_Queen_Margaret.html
Empress Dowager Cixi, of the Manchu Yehenara clan, was a powerful and charismatic woman who unofficially but effectively controlled the Manchu Qing Dynasty in China for 47 years, from 1861 to her death in 1908.