Visceral hypersensitivity syndrome is one proposed cause of IBS. That's when the signal between your bowels and brain is TOO LOUD! That leads to excess pain and other IBS symptoms.
Inflammation of the lining of the intestinal wall causes Inflammatory Bowel Diseases (IBD) such as diverticulitis, ulcerative colitis, and Crohnâ€™s disease. These diseases are painful and can cause acute diarrhea, fever, fatigue, reduced appetite, weight loss, and blood in the stools. To soothe the lining of the intestines, doctors often recommend following a low residue diet or a low fiber diet.
Normal vs. ischemic colitis. The classic histologic features of (early) ischemia are present in this image: surface-predominant changes including shrunken (microcystic) crypts lined by flattened, goblet cell-deficient epithelium, eosinophilic lamina propria with relatively little inflammation, and necrosis of surface epithelium