David Bowie has a condition called anisocoria, which is the medical term for unequal pupils. At he got punched in the eye by his schoolfriend, which caused his pupil to remain permanently open. Some people think his irises are two different colors.
David Bowie, Beautiful People, Memories, Rock, Happy
Bowie as Mephistopheles ♥ from the opera Faust by Charles Gounod. Bowie is wearing a slightly altered version of traditional garb, wearing long breeches that come down to his knees with stockings, with a jerkin worn under his cloak/jacket